FAQs from Battersea patients
Common questions.
Is the salmon sperm facial the same as polynucleotides?
Yes. Polynucleotides are purified DNA fragments (PDRN) derived from salmon or trout milt, which is where the nickname comes from. The material is purified to remove protein before it is used, so nothing living is injected and it is not sperm in any meaningful sense. You may also see it called salmon DNA, PDRN, or a brand name such as Nucleofill. It is a biostimulator rather than a filler, so it changes skin quality rather than adding volume, and results build over a course. Individual results vary.
How much do polynucleotides cost in Battersea?
At Melatone, Nucleofill polynucleotides are a Course of 3 at £540 (£180 per session, three sessions four weeks apart per the published protocol), or £200 for a single session. The same £540 course price applies to the eye area, full face and hair. A £30 consultation is deducted from your first treatment.
Where can I book polynucleotides in Battersea or Clapham?
You can book polynucleotides at Melatone Skin Clinic in Battersea SW11, 10 to 14 minutes on foot from Clapham Junction and serving Clapham and South West London. Nucleofill polynucleotides are delivered by Arman Zaki, our founder and GMC-registered Physician Associate. Book a consultation through the Treatwell widget on this site, or message us on WhatsApp at +44 7586 817215 to arrange it.
Who delivers polynucleotides at Melatone?
Arman Zaki, our GMC-registered Physician Associate. He is trained in regenerative skin therapy and delivers Nucleofill polynucleotides.
Are polynucleotides safe for darker skin tones?
Yes, when delivered by a clinician experienced in melanated skin, polynucleotide injectables are generally well tolerated across Fitzpatrick skin types IV, V and VI. Because they are not a light-based treatment, they do not carry the wavelength-related risks that laser can pose for deeper skin tones. The main consideration in pigmented skin is post-inflammatory hyperpigmentation (PIH), which the literature identifies as the key parameter to manage. We minimise that risk with conservative injection technique, fewer passes, needle depth calibrated to each zone, a Fitzpatrick assessment at consultation, and a healing-response check at follow-up. We are honest about the evidence: there is strong category-level research on polynucleotides, but no large product-specific trial dedicated to melanated skin, so we lead with cautious technique and careful patient selection rather than overclaiming. Polynucleotides are not suitable for everyone, and individual results and suitability vary. If your main concern is existing pigmentation such as melasma, we will tell you honestly at consultation whether polynucleotides, another treatment, or none is the right fit.
How close is Melatone to Clapham Junction?
10 to 14 minutes on foot from Clapham Junction, or a short bus down Lavender Hill. South side of Lavender Hill at the junction with Latchmere Road, Battersea Business Centre, SW11 5QL. Battersea Park station is also nearby.
Polynucleotides vs filler, what is the difference?
Different mechanisms. Filler adds volume by physical displacement. Polynucleotides stimulate your own fibroblasts to improve skin quality over weeks. They are complementary, not interchangeable. We will tell you which one fits your goal at consultation.
Where can I read the clinical evidence for polynucleotides?
The polynucleotide (PDRN) regenerative-aesthetics literature is indexed on PubMed. Specialist sources include the Journal of Regenerative Aesthetic Medicine (JRAM) and the Journal of Aesthetic and Regenerative Medicine (JARM). This page is general information, not a substitute for a consultation.
When will I see results?
Most patients notice skin texture and hydration improvement after the second session. Full result typically peaks 8 to 12 weeks after the third session. Maintenance every 6 to 9 months.
What are the benefits of polynucleotides for skin rejuvenation?
Polynucleotides (Nucleofill) stimulate your own fibroblasts, the cells that build collagen and elastin. Over a course they improve skin quality, texture, hydration and firmness, and are widely used around the eyes. Results build over weeks and vary between individuals.
Are polynucleotides or Profhilo better for improving skin quality?
They work differently. Polynucleotides (Nucleofill) prompt your own fibroblasts to repair and rebuild, so they suit skin quality, texture and under-eye concerns. Profhilo is a hyaluronic acid bio-remodelling treatment that hydrates and firms. They are complementary, and we advise which fits your goal at consultation.
